For more information, please see our Topamax information for Healthcare Professionals. Topiramate is a second-generation antiepileptic drug that is used in the treatment of seizure disorders and migraine headaches. I'm taking it to help control seizures. Learn the causes, treatments, and remedies for this type of headache. It is labeled for blood pressure, but I get it for off label OCD/SSRI intolerance. This can include setting an alarm or using a timer. bruising under the skin. You can take Topamax with food or without it. Food & smells have been really off too will this adjust this itself out? Drinking alcohol while taking Topamax can increase your risk of certain side effects and increase the chance that theyll be serious. No matter the type of carbonated beverage, each one tasted flat to her since starting topiramate therapy. In studies, this side effect was more common in people who took the drug to treat epilepsy than to prevent migraine headaches. Official answer. Through sensory nerves, the receptors communicate information about tastes to the brain. They may recommend ways to ease your symptoms and determine whether you should keep taking Topamax. A bitter or bad taste in the mouth can occur after eating pungent or sour foods, but it can also stem from hormonal changes, poor oral health, medication use, stress, and many other factors. Taking Topamax can cause hair loss as a side effect. Just an FYI I didn't start to lose my hair until I was on 150mg of the topamax. Talk with your doctor to learn if Topamax is right for you. Be sure to talk with your doctor and pharmacist about all of the drugs you take before starting Topamax. Learn more. So you may have migraine headaches or seizures more often, or they may be more severe. Taking Topamax while pregnant increases the childs risk of a cleft lip or cleft palate. Treat epilepsy * in. Do not break, crush, or chew it. I want real experience please not someone posting side effects to the medicine as I've read those already. This side effect was somewhat common in clinical trials. Department of Pharmacy Practice, Western New England University College of Pharmacy and Health Sciences, Address correspondence to Dr. Charbonneau (. They may also recommend that you visit an eye doctor. Talk with your doctor about the best way to feed your child if youre taking Topamax. You may have mild side effects from Topamax. You should not drink alcohol while youre taking Topamax. Liver problems could raise your risk for a high level of ammonia in your blood, which is a possible side effect of Topamax. Your doctor can help determine whether treatment with Topamax is safe for you. This could raise your risk for having a high level of acid as a side effect of Topamax. Aswini YB, Tangade PS, Ankola AV et al. The list below may not include all possible serious side effects of the drug. Case assessment using the adverse drug reaction probability scale of Naranjo et al15 indicated a probable relationship between topiramate use and carbonation-perception loss (ie, a score of 5). Or they may suggest you wean off Topamax and try a different treatment for your condition. it was my drink. Promptly after the initiation of topiramate, the patient lost her ability to taste carbonation in all beverages, including soda, seltzer, and beer. Cookie Notice You may be at higher risk if you already experience depression or suicidal thoughts. And its not likely to cause liver problems unless youre also taking other drugs that can harm your liver. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Topamax (topiramate) tablets, for oral use; Topamax (topiramate capsules) sprinkle capsules, for oral use. Mild side effects that have been reported with Topamax include: burning or numbness in your hands and feet appetite loss speech problems fatigue dizziness * sleepiness nervousness memory. The patient reported good adherence to the medication, missing less than 1 dose per month. it totally sucks. It completely knocks out the effects of the phentermine. Topamax can be prescribed for weight loss. Oxford University Press is a department of the University of Oxford. Donegan et al13 performed a systematic review of 90 placebo-controlled trials of topiramate and noted that dysgeusia was reported at a significantly higher rate with topiramate vs placebo use. Topamax can cause certain stomach-related side effects. In this line of thought, zinc supplementation may be needed with carbonic anhydrase inhibitor administration to prevent or treat dysgeusia. Apparently it does make soda taste weird!!!!!!!!!!! Possibly. And your doctor can use this information to adjust your treatment plan if needed. and our Yes, Topamax may cause sexual side effects, such as decreased sex drive. Examples include hair loss and eye problems. * This side effect can affect your ability to drive or safely operate machinery. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. You may remove weapons or substances that can cause harm if you can do so safely. In clinical studies, some people had fewer headaches after 4 weeks of treatment. They can help answer any questions you have about side effects from taking the drug. Call 911 or the local emergency number, or text TALK to 741741 to communicate with a trained crisis counselor. How long does it take for Topamax to start working? Examples of behavior and mood shifts Topamax can cause include: If you have any unusual shifts in mood while taking Topamax, call your doctor right away. For people ages 12 and older, the recommended total daily dose for preventing migraines is 100 mg per day, divided into two doses. Its important to note that the dosage of Topamax is higher for seizures than for migraine headache prevention. For example, missing Topamax doses could cause you to have a migraine headache. Although rare, Topamax can also cause a glaucoma attack. Mild side effects that have been reported with Topamax include: These side effects may be temporary, lasting a few days or weeks. Specifically, the drug can cause decreased growth in children. ', Can someone tell me if I will ever enjoy Coca Cola ever again? Read on to learn about potential common, mild, and serious side effects. Can I take Aleeve if I'm on Topamax (topiramate)? If taken during pregnancy, the drug can cause side effects in children. Educational text answers on HealthTap are not intended for individual diagnosis, treatment or prescription. South-facing chalet in the municipality of Villard sur Doron. Topamax dosage for migraines. The topiramate level was not rechecked after the first determination 17 days after topiramate initiation. This may make some side effects more likely. You should not drink alcohol while taking Topamax. Some of these side effects are mild, while others can be more serious. See additional information. Does metabolism change or just taste for foods/amts? Topamax (topiramate) is a brand-name anticonvulsant drug that works in the brain to prevent seizures. And some may be easily managed, too. In rare cases, Topamax can cause metabolic acidosis (too much acid in your blood). Call your doctor or 911 if you think you may have a medical emergency. If you are not in the same household, stay on the phone with them until help arrives. I secretly thought I had covid because one of the symptoms is your taste buds going crazy. How long does Topamax stay in your system. If you have questions about side effects from Topamax, talk with your doctor or pharmacist. Soda still tastes strange. UPDATE: OMFG! Symptoms of these conditions may include: Tell your doctor right away or go to the nearest emergency room if you notice any of the above symptoms while youre taking Topamax. During a crisis, people who are hard of hearing can use their preferred relay service or dial 711 then 988. Not to mention it took that long for the word slurring feeling and brain fog to go away. If the side effects seem life threatening or if you think youre having a medical emergency, immediately call 911 or your local emergency number. A systematic review of placebo-controlled trials of topiramate: how useful is a multiple-indications review for evaluating the adverse events of an antiepileptic drug? Although the sense of carbonation when drinking with a straw was not as intense as it was prior to topiramate initiation, she noticed considerable improvement; the straw enhanced the carbonation taste sensation enough to make some carbonated beverages palatable.. They can help you figure out if youre having other mood changes that could cause these side effects. Ocular (eye-related) side effects may occur with Topamax. A 39-year-old Caucasian woman with epilepsy had a generalized seizure after 12 years without use of antiepileptic medication. I was wondering what foods taste different to you since taking Topamax? Talk with your childs doctor, or a pharmacist, if you have questions about Topamaxs side effects in children. Still looking for answers? We avoid using tertiary references. 2023 Healthline Media LLC. .it is the topamax. If you have thoughts of harming yourself while taking Topamax, call 911 or your local emergency number right away. They can recommend ways to reach or maintain a weight thats healthy for you. For these, please consult a doctor (virtually or in person). Below we provide information about Topamax and pregnancy and breastfeeding. everything tastes wrong, kind of like metal. 1. HealthTap uses cookies to enhance your site experience and for analytics and advertising purposes. They will help keep your hair in great shape and keep it on your head. Symptoms can include: feeling agitated, aggressive, or irritable, losing interest in activities you normally enjoy, Ask the tough question: Are you considering suicide?. In most cases, eye side effects go away if you stop taking the drug. Treatment involves addressing the underlying cause of dysgeusia. Treatment with Topamax can cause a variety of cognitive side effects. In addition, weight and height may be affected in children taking Topamax. Call your doctor if you have changes in taste while taking Topamax. The pain can be so severe that it becomes debilitating. Here we describe a case of carbonation dysgeusia potentially related to the initiation and continued use of topiramate following a generalized seizure. High blood levels of ammonia (a waste product made by your body), which may cause swelling in your brain. And do not stop using Topamax unless your doctor recommends it. If you have questions about possible long-term side effects of Topamax, talk with your doctor or pharmacist. UPDATE: OMFG! I am not a fan. Never disregard or delay professional medical advice in person because of anything on HealthTap. However, the drug can also cause some serious side effects which may require treatment. For more information, you can refer to Topamaxs prescribing information. The conditions and factors to consider include: Bone problems, such as osteoporosis. Linde et al11 noted a significant difference in taste disturbance adverse effects with topiramate vs placebo use in a meta-analysis of 9 trials involving a total of 1,737 participants. For a general overview of the drug, including details about its uses, see this article. It all tastes weird & just bad, like an awful stinging, metallic taste on my tongue. Doing so can worsen certain side effects of Topamax, such as dizziness and sleepiness. Healthline Media does not provide medical advice, diagnosis, or treatment. Privacy Policy. ! Serious side effects that have been reported and their symptoms include: * For more information about this side effect, see Side effect specifics below. However, I'm really losing weight. Is the ketogenic diet right for autoimmune conditions? Changes in taste was a common side effect reported by people who took Topamax for preventing migraine headaches in clinical trials. Having diarrhea like this could raise the level of acid in your blood, which may increase your risk of a high acid level in your blood as a side effect of Topamax. They may suggest medication to manage your symptoms. A throbbing headache can occur due to migraine, tension, or neuralgia. Are there any side effects of Topamax that I should tell you about right away? Topiramate is used alone or with other medications to prevent and control seizures ( epilepsy ). Gabapentin can help control seizures as well as nerve pain from shingles. For more information about this side effect, see Side effect specifics below. It is hard while you are building up. what were you taking it for if you don't mind me asking? I do not think it is the same for seizure treatment. Oh, yeah. Below are a few questions you may want to ask: If you have migraine, consider signing up for Healthlines online newsletter. These symptoms could be life threatening and require immediate medical care. However, if your symptoms are serious and you think youre having a medical emergency, immediately call 911 or your local emergency number. This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (. Swallow the food mixture right away without chewing. Taste . Below are answers to a few frequently asked questions about Topamaxs side effects. Topamax can increase your risk of depression and suicidal thoughts or actions. This condition causes sudden, severe eye pain and blurry vision. I've had minimal side effects -- lots of drinks and foods tasted strange at first, some low-grade headaches for the first couple of months -- but they've mostly disappeared. Overall these things don't bother me. This can cause foods to taste different or bad. The patient looked to online forums for patients with epilepsy and migraine for information on the phenomenon and found numerous reports of similar experiences from others taking topiramate on the websites epilepsy.org and migraine.org.9,10 In one such forum, someone suggested using a straw to help mitigate the adverse effect, and our patient found the suggestion helpful. The authors have declared no potential conflicts of interest. Learn more. Allergic reaction. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. In rare cases, Topamax can cause metabolic acidosis, which can lead to kidney stones if it isnt treated. It may not be safe to use Topamax while breastfeeding. Case assessment using the adverse drug reaction probability scale of Naranjo et al indicated that topiramate was the probable cause of the patients carbonation taste perversion. Joeyshoney mood changes (see Mood changes just above), swelling under your skin, typically in your lips, eyelids, feet, or hands, swelling of your mouth, tongue, or throat, which can make it hard to breathe. Talk with your doctor about the possible risks of taking Topamax if youre pregnant or planning a pregnancy. Talk with your doctor about which other treatments are better choices for you. Having reduced BMD could indicate that you have weakened bones. Find out whats causing frothy saliva and how to, Melatonin can be a successful natural sleep aid. Dysgeusia can be caused by many different factors, including infection, some medications and vitamin deficiencies. 2023 Healthline Media UK Ltd, Brighton, UK. Botox (onabotulinumtoxinA) is a prescription drug used for several conditions. If you develop a side effect while taking Topamax and want to tell the FDA about it, visit MedWatch. Perhaps with a straw the carbonated beverage is more concentrated on the tongue, where taste is perceived. They both tasted just fine before I started on topamax. Maybe that's not the best description but it definitely tastes weird. It may not be safe to take Topamax while pregnant. Most side effects tend to go away soon after you start or stop taking the drug. Reddit and its partners use cookies and similar technologies to provide you with a better experience. Although topiramate has multiple mechanisms of action, its carbonic anhydrase inhibitory effects are similar to those of acetazolamide.17. If you have bone problems before starting Topamax treatment, you may have a higher risk of bone problems related to high acid levels. Like most drugs, Topamax can cause an allergic reaction in some people. The term carbonation dysgeusia is used to describe distortions of carbonation taste quality leading to diminished or complete elimination of the pungency or prickly sensation experienced on imbibing carbonated beverages.8 Other cases of topiramate-induced carbonation dysgeusia have been widely mentioned in various Internet patient forums.9,10 Although topiramate-induced dysgeusia has been reported in numerous randomized controlled trials, most of the trial reports did not define the specific manifestation of dysgeusia.11-13 Furthermore, our PubMed search, conducted without date limits using the terms topiramate and carbonation dysgeusia or drug-induced taste perversion, identified no previous reports describing this reaction in detail. Having diarrhea while taking Topamax can increase your risk of metabolic acidosis. Talk with your childs doctor about your childs risk of side effects from Topamax. Keep reading to learn about the common, mild, and serious side effects of Topamax and ways to deal with them. It is difficult to ascertain exactly why use of a straw may enhance carbonation perception in the mouth. Examples include: If you have more questions about your risk of certain side effects from Topamax, talk with your doctor or pharmacist. How should I manage side effects I may have from Topamax. Lowered BMD could mean your bones are weakened. This list doesnt include all possible mild side effects of the drug. If youd like to learn more about Topamax, talk with your doctor or pharmacist. Side effects in clinical trials were slightly different depending on whether people used the drug to treat seizures or to prevent migraine headaches. Following a ketogenic (keto) diet. Frequent diarrhea. Although not common, Topamax can cause eye problems. Your doctor can help determine whether treatment with Topamax is safe for you if you have kidney problems. These side effects can vary depending on which condition the drug is being used to treat. Kidney problems may increase the level of acid in your blood. Serious side effects that have been reported with Topamax include: If you develop serious side effects while taking Topamax, call your doctor right away. If you drink alcohol and have questions about Topamaxs alcohol interaction, talk with your doctor. Youll get first-hand stories from people living with this condition as well as tips for managing symptoms. This side effect wasnt common in clinical trials and was only reported by people taking the drug for epilepsy. Hello doctor, I am on topamax (topiramate) and i've lost between 5-10 pounds in just 2 weeks is this healthy? More common side effects in people taking Topamax for migraine include: More common side effects in people taking Topamax for epilepsy include: Read on to learn about other mild and severe side effects that can happen with Topamax. Some side effects can cause long-term effects if they arent treated, such as increased pressure in your eye. The suggestion of drinking carbonated beverages through a straw to mitigate carbonation dysgeusia is an interesting recommendation. Theyll recommend whether you should stop taking the drug. Before taking Topamax, tell your doctor if you have mood problems such as depression. Kidney problems. Examples of mild side effects that have been reported with Topamax include: * To learn more about this side effect, see the Side effects explained section below. 1 more week and I'm finished. Ask your doctor what other medications are better options for you. Topamax is used to prevent migraine headaches and treat epilepsy in certain people. Topamax can cause certain side effects, some of which are more common than others. You can learn more about how we ensure our content is accurate and current by reading our. "Thankfully, this is normally a temporary problem," Dr. Kaye says. These side effects can vary depending on which condition the drug is being used to treat. Click here for more links and local resources. Good if you want to lose weight. For me (i was eventually on 250 mg for migraines) every time I increased my dose I had those symptoms for about 2 or 3 days and then would subside until my next increase.I did discuss the anxiety with my Dr. and he prescribed xanax which helped a lot. Examples include Stevens-Johnson syndrome and toxic epidermal necrolysis. If you have kidney problems, such as chronic kidney disease, you have an increased risk of both metabolic acidosis and kidney stones as a complication. Is this a side effect? In most cases, side effects from Topamax are temporary. Thank you for submitting a comment on this article. Glaucoma. Children are less likely than adults to experience the following side effects from Topamax: Also, children taking Topamax may experience decreased bone mineral density (BMD). If the side effects seem life threatening or you think youre having a medical emergency, immediately call 911 or your local emergency number. Find a helpline in your country with. This includes conditions such as asthma and chronic obstructive pulmonary disease (COPD). You may have changes in your sense of taste as a result of taking Topamax. These results were consistent with results of bloodwork performed years previously; at that time, her bloodwork indicated all evaluated levels were within normal limits except for low concentrations of ALP (40 U/L) and creatinine (0.6 mg/dL). Also , will my soda always taste bad while on it? Dysgeusia is a medical condition defined as an alteration of the sense of taste.1 Certain medications can lead to dysgeusia through various mechanisms of action involving chemosensory pathways, such as taste, smell, and salivation.2 The majority of cases of taste dysfunction due to medication use cited in the literature involved hypogeusia (partially impaired sense of taste) or the more general dysgeusia.3 Dysgeusia has been reported with use of antibiotics (eg, clindamycin, metronidazole, fluoroquinolones), neurologic medications (eg, central nervous system stimulants, muscle relaxants), and psychotropics (eg, tricyclic antidepressants, anxiolytics, mood stabilizers) as well as antihistamines, antineoplastics, smoking cessation aids, and antifungals, among others.4, Metallic taste following medication administration is a commonly reported medication-induced dysgeusia. If you have symptoms of a severe allergic reaction, such as swelling or trouble breathing, call 911 or your local emergency number right away. Angiotensin-converting enzyme inhibitors, especially captopril, are among the drugs most commonly associated with taste disturbances, with strongly metallic, bitter, or sweet tastes having been reported.6. But this side effect wasnt reported in studies. If you have questions about Topamax and hair loss, talk with your doctor or pharmacist. Luykx J, Mason M, Ferrari MD, Carpay J. Donegan S, Dixon P, Hemming K, Tudur-Smith S, Marson A. Naranjo CA, Busto U, Sellers EM et al. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. a common cold. Topamax making carbonated drinks taste flat? Although research is ongoing, CBD is currently approved to treat seizures caused by two rare forms of epilepsy and tuberous sclerosis complex. All rights reserved. Did anyone experience things tasting weird afterwards? Anticholinergic medications are associated with dry mouth, which can be interpreted as a metallic taste. I am currently almost off Topamax now. But taking the drug with food may help lessen any stomach problems you have. See the Topamax prescribing information for details. I put up with the side effects for a year because it worked but when it stopped working it was no longer worth it for me. At the time of dysgeusia development, topiramate was the only medication the patient was taking; thus there seems to have been a clear temporal relationship between topiramate use and the onset of her symptoms. Taking Topamax while pregnant can cause harm to the fetus. The 988 Suicide and Crisis Lifeline is available 24 hours a day at 988. However, compared to adults, children taking Topamax may be more likely to have certain side effects, including: Its important to keep an eye on your child in hot weather. If a child takes Topamax, their doctor will check their growth. Soda taste flat and chocolate taste bitter. Examples include hair. Your doctor can recommend whether Topamax is safe for you to take. Connect with a U.S. board-certified doctor by text or video anytime, anywhere. And this could increase your risk for having a high level of acid as a side effect of Topamax. Does Topamax cause long-term side effects or permanent side effects? The main thing for me has always been an aversion to pop/soda. Its also important to know that suddenly stopping Topamax could cause or worsen seizures. However, its not clear whether this side effect occurred in clinical trials. Topamax doesnt rely heavily on your liver to help remove it from your body. i'm on it and cannot drink anything with bubbles. The drug can cause side effects such as sleepiness or diarrhea in a breastfed child. Ok so I drink a crap ton of Coca Cola and for some reason it taste like it has Vodka in it lol. Highlights of prescribing informationTopamax, A method for estimating the probability of adverse drug reactions, Topiramate in the treatment of partial and generalized epilepsy, Topiramate as an inhibitor of carbonic anhydrase isoenzymes, Carbonic anhydraseIV mediates the fizz of carbonated beverages, Side effects of acetazolamide: the champagne blues, Altered taste secondary to acetazolamide therapy, Energy and nutrient consumption of patients with dysgeusia, The effect of different methods of drinking a carbonated beverage on the pH of dental plaque: an in vivo study, Preventive effects of zinc sulfate on taste alterations in patients under irradiation for head and neck cancers: a randomized placebo-controlled trial. * To learn more about this side effect, see the Side effects explained section below. And this could increase the chances of Topamax causing a high level of acid as a side effect. dry mouth. Topamax is an appetite suppressant and studies confirm Topamax does cause significant weight loss. An allergic reaction is possible after using Topamax. Find out what's popular at Intermarch Contact in Villard-sur-Doron, Auvergne-Rhne-Alpes in real-time and see activity Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. By 4 pm I'm. Most of the participants did lose weight while on the drug, significantly more than the placebo group, however, the side effects discouraged some from continuing the trial. This measurement describes bone strength. The taste of food/drink however will remain the same the entire time you are on Topamax no matter what the dose. Here are some frequently asked questions about the drugs side effects and their answers. Maheswaran T, Abikshyeet P, Sitra G, Gokulanathan S, Vaithiyanadane V, Jeelani S. Linde M, Mulleners WM, Chronicle EP, McCrory DC. Call 911 or your local emergency services number if you feel safe to do so. Talk with your doctor to learn if Topamax is right for you. Zinc may play a role in taste perception, and zinc deficiencies may contribute to taste disorders.24 There is evidence to support the use of zinc supplementation in some cases of medication-induced dysgeusia. Your doctor may monitor your acid levels more closely than usual during treatment. Which can be very dangerous and just plain weird. Examples of mood changes you may notice while taking Topamax include: Tell your doctor right away if you have mood changes while taking Topamax. Lung problems. But if you have any symptoms that are ongoing or that bother you, talk with your doctor or pharmacist. Talk with your doctor if you experience cognitive side effects while taking Topamax. Folic acid is also a great supplement. The agitation & irritability though has been slightly intense the last 2 days so I'm really hoping this will balance out. The following day, the patient was seen by her primary care physician, who switched from levetiracetam to topiramate 25 mg by mouth twice daily, with titration to topiramate 100 mg by mouth twice daily for maintenance therapy after 3 weeks. 1. For these reasons, you should not stop taking Topamax unless your doctor tells you its safe to do so. Most people with epilepsy have warning signs during the prodromal or aura stages of a seizure, allowing extra time to get help.
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